Royal Air Force Typhoon fighter aircraft have operated alongside French warplanes in a joint strike against an hidden munitions depot in Syrian territory employed by the IS group, as stated by the UK's MoD.
The location, identified by surveillance, was thought to be storing arms and explosives, the statement said, and was located in hills just north of Palmyra in central Syria.
"The RAF jets used Paveway IV guided bombs to target a number of approach shafts leading to the facility... preliminary assessments indicate the target was engaged successfully," the MoD said.
There was no sign of any harm to civilians in the attack on Saturday evening and every plane involved returned safely, the defence officials confirmed.
The Typhoon FGR4s were backed up by a Voyager tanker plane.
The Islamic State group - alternatively referred to as Daesh - imposed militant control over parts of Iraq and Syria prior to its 2019 collapse.
"This strike shows British leadership, and determination to work closely with our allies, to eliminate any re-emergence of IS and their violent and radical beliefs in the region," the British Defence Secretary the minister stated.
UK warplanes have performed patrols over Syria to "forestall any attempted comeback" of the group after its routing at the climactic battle in Baghuz in 2019, the authorities noted.
"I want to thank the personnel of British forces who took part in this mission for their skill and their valour," the Defence Secretary said. "They were part of a great many British troops stationed over the festive period. This mission, to eliminate dangerous terrorists who threaten our security, shows how our armed forces are prepared to act, continuously, protecting the UK domestically and influential overseas."
Last December, the US military executed what it described as a "large-scale strike" targeting IS targets in Syria, subsequent to an ambush claimed the lives of two US servicemembers and a local interpreter in the Palmyra area.
The U.N. reports Daesh still boasts an estimated 5,000 to 7,000 militants in Syria and Iraq.